A region of interest on a heart wall of a heart chamber of the heart is three-dimensionally expressed and recorded on a two-dimensional image. An image processing apparatus according to the present invention images a heart chamber from a predetermined direction. An image processing unit that generates a second two-dimensional image in which a marker indicating a predetermined region of interest on the heart wall of the atrioventricle is superimposed on the first two-dimensional image based on the obtained fluoroscopic image； And an acquisition unit that acquires position information of the site of interest including the depth direction, and the image processing unit changes the mode of the marker indicating the site of interest based on the position information of the site of interest. [Selection] Figure 1【課題】心臓の房室の心壁上の関心部位を二次元画像上で三次元的に表現・記録する【解決手段】本発明に係る画像処理装置は、心臓の房室を所定方向から撮像したＸ線透視画像に基づく第１の二次元画像に、房室の心壁上の所定の関心部位を示すマーカを重畳した第２の二次元画像を生成する画像処理部と、所定方向から見た奥行き方向を含む、関心部位の位置情報を取得する取得部と、を備え、画像処理部は、関心部位の位置情報に基づき、該関心部位を示すマーカの態様を異ならせる。【選択図】図１
