The Trustees of The University of Pennsylvania;Novartis AG
发明人:
申请号:
EP19219069.2
公开号:
EP3712171A1
申请日:
2015.08.19
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The invention provides compositions and methods for treating diseases associated with expression of CD123. The invention also relates to chimeric antigen receptor (CAR) specific to CD123, vectors encoding the same, and recombinant cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified cell expressing a CAR that comprises a CD123 binding domain.