The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人:
Hoon Mark A.,Mishra Santosh K.
申请号:
US201415039982
公开号:
US9987330(B2)
申请日:
2014.12.04
申请国别(地区):
美国
年份:
2018
代理人:
Leydig, Voit & Mayer, Ltd.
摘要:
Disclosed is a method of treating, reducing, or preventing pruritis in a mammal, the method comprising administering at least one natriuretic polypeptide b (Nppb) blocking agent to a mammal in an amount effective to treat or prevent pruritis in the mammal. An in vitro method of identifying a compound that inhibits Nppb activity is also disclosed.