The invention relates to a hops-based substance which comprises a mixture of (a) xanthohumol with the formula (1) and (b) at least one isomerized hops acid, preferably iso-alpha acid, in each case in a concentrated or isolated form. It has surprisingly been shown that a substance in which xanthohumol and iso-alpha acid are present in combination and in which each substance is present in a concentrated or isolated form in the combination substantially increases the effectiveness in conjunction with the prevention and/or control of liver diseases or liver damage when compared to xanthohumol alone. The inflammation- and fibrosis-inhibiting effect of xanthohumol and the inhibition of the fatty changes of liver cells is thus surprisingly increased by the presence of iso-alpha acid.
