SHAH, CHITRA,GUAL-PUJOL, FRANCISCO,AMELA-NAVARRO, JOAQUIM,RUIZ-CÓRDOBA, JOSÉ LUIS
申请号:
PL09159296
公开号:
PL2255791T3
申请日:
2009.05.04
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
An extended release pharmaceutical composition comprising metoprolol succinate and at least two pharmaceutically acceptable excipients, wherein one pharmaceutically acceptable excipient is an extended release agent; the second pharmaceutically acceptable excipient is selected from a binder, a diluent and mixtures thereof; and metoprolol succinate is in a crystalline form having a D50 ranging from 5 to 16 microns and a D90 below 50 microns.