An X-ray diagnosis apparatus of an embodiment includes: an imaging unit that includes an X-ray tube which emits an X-ray to a subject, and an X-ray detector which detects an X-ray passing through the subject an X-ray beam limiting unit that is disposed between the X-ray tube and the X-ray detector, has a plurality of collimator blades, and can be rotated an image processing unit that generates a fluoroscopic image of a region of interest set by the X-ray beam limiting unit and a control unit that individually controls the plurality of collimator blades in such a way that a long side of an opening formed by the plurality of collimator blades goes in a longitudinal direction of a target within the fluoroscopic image.