The Salk Institute for Biological Studies;Universität Bern Verwaltungsdirektion;University Hospital Basel
发明人:
RIVIER, JEAN E.F.,ERCHEGYI, JUDIT,REUBI, JEAN CLAUDE,MAECKE, HELMUT R.
申请号：
PL11173287
公开号：
PL2383289T3
申请日:
2007.10.15
申请国别(地区):
PL
年份:
2015
代理人:
摘要：
This invention is directed to peptides related to somatostatin and to methods for pharmaceutical treatment of mammals using such peptides. More specifically, the invention relates to shortened receptor-selective somatostatin peptide antagonists and the inclusion of amino acid substitutions and/or additions in such peptides that confer receptor-selectivity thereto, to pharmaceutical compositions containing such peptides, to such peptides complexed with or conjugated to radioactive nuclides, to methods of diagnostic and therapeutic treatment of neoplastic and non-neoplastic mammalian diseases using such peptides, particularly peptides that are coupled to chelators or otherwise labeled, and also to methods for screening for more effective drugs using such peptides.
