Aniline derivatives, their preparation and their therapeutic application as EP2 agonists in, for example, glaucoma.R1 represents, independently from each other, H, a (C1-C6) alkyl or an halogen,R2 represents H, an halogen, or a (C1-C6) alkyl,R3 represents, independently from each other, H, an halogen, -OH, -O-(C1-C6) alkyl or a -(C1-C6) alkyl.