Phenylacetic acid derivative (2,3-d) pyridine hydroxyhydrazide, used in the treatment of propylene and autoimmune diseases, its preparation method and pharmaceutical components containing the substance
Bálint, Balázs,Chanrion, Maïa,Davidson, James Edward Paul,Geneste, Olivier,Kotschy, András,Murray, James Brooke,Paczal, Attila,Proszenyák, Ágnes,Sipos, Szabolcs,Szlávik, Zoltán
申请号:
CU20170162
公开号:
CU20170162A7
申请日:
2016.06.22
申请国别(地区):
CU
年份:
2018
代理人:
摘要:
<;p>; The present invention relates to compounds derived from phenyl-thieno (2,3-D) pyrimidine-hydroxy acid, useful in the treatment of cancer and autoimmune diseases, of formula (I): <;/p>; <;p>; SPACE FOR FORMULA <;/p>; <;p>; in which R1, R2, R3, R4, R5, R6, R7, R8, R14, A and n are as defined in the description. The invention further relates to the form of preparation of said compounds and to the pharmaceutical compositions containing them. <;/p>;<;p>;La presente invención se refiere a compuestos derivados de fenil-tieno(2,3-D)pirimidina-hidroxiácido, útiles en el tratamiento del cáncer y enfermedades autoinmunes, de fórmula (I):<;/p>; <;p>;ESPACIO PARA FÓRMULA<;/p>; <;p>;en Ia que R1, R2, R3, R4, R5, R6, R7, R8, R14, A y n son como se han definido en la descripción. La invención se refiere además a la forma de preparación de dichos compuestos y a las composiciones farmacéuticas que los contienen.<;/p>;