PROBLEM TO BE SOLVED: To provide therapeutic agents for diseases associated with skeletal muscle degeneration, particularly muscular dystrophy, and to provide administration methods thereof.SOLUTION: The invention provides a therapeutic agent containing a granulocyte-colony stimulating factor (G-CSF) as an active ingredient. The invention also provides a method for treating diseases associated with skeletal muscle degeneration, particularly Duchenne muscular dystrophy, by a therapy selected from inhibiting muscular degeneration, promoting regeneration, inhibiting the progression of muscular weakness, inhibiting the collapse of muscle fibers, increasing the ratio of regenerative muscle fibers, increasing muscles, and enhancing the athletic ability of muscles.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】骨格筋の変性を伴う疾患、特に筋ジストロフィーの治療剤及びその投与方法の提供。【解決手段】顆粒球コロニー刺激因子(G-CSF)を有効成分として含有する治療剤。筋肉の変性を抑制、再生を促進、筋力低下の進行を抑制、筋線維の崩壊を抑制、再生筋線維の割合を増加、筋肉を増大、及び筋肉の運動能力を高めることから選択される治療によって、骨格筋の変性を伴う疾患、特にデュシェンヌ型筋ジストロフィーの治療を行う方法。【選択図】なし