Ying Sun,Deqiang Niu,Guoyou Xu,Yat Sun Or,Zhe Wang
申请号：
US12016643
公开号：
US08268776B2
申请日:
2008.01.18
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
