POLYBACTERIAL PREPARATION WITH HEALTH BENEFITS: ANTIOXIDANT EFFECT, REDUCTION OF CHOLESTEROL CONCENTRATION, ANTI-INFLAMMATORY IMMUNOMODULATING EFFECT AND RELEASE OF BIOACTIVE PEPTIDES INHIBITING ANGIOTENSIN-CONVERTING ENZYME
This invention relates to polybacterial probiotic preparation, which includes new strains of lactic acid bacteria Lactobacillus gasseri 7/12 NBIMCC No. 8720, Lactobacillus plantarum F12 NBIMCC No 8722 and Lactobacillus helveticus Al, NBIMCC No 8721 and has the following set of properties : antioxidant, hypocholesterolemic effect, anti-inflammatory immunomodulating effect, ability to release bioactive peptides that inhibit angiotensin-converting enzyme (ACE), which is responsible for the high blood pressure. The object of invention is also the described probiotic strains of lactic acid bacteria and the developed bacterial products with useful properties. The incorporated probiotic strain Lactobacillus gasseri 7/12 NBIMCC No. 8720, has a number of properties: strong adhesion to the epithelial layer of the colon, the ability for reduction of cholesterol and anti-inflammatory effects by reducing the levels of proinflammatory cytokine interleukin-8. The invention relates to the use of strains of lactic acid bacteria and bacterial agents in the production of starter cultures, food additives, food, functional products and pharmaceutical preparations intended to influence the health of humans and animals.La présente invention concerne une préparation probiotique polybactérienne comprenant des nouvelles souches de bactéries dacide lactique Lactobacillus gasseri 7/12 NBIMCC No. 8720, Lactobacillus plantarum F12 NBIMCC No 8722 et Lactobacillus helveticus Al, NBIMCC No 8721, laquelle préparation présente lensemble des propriétés suivantes: anti-oxydante, effet hypocholestérolémique, effet immunomodulateur anti-inflammatoire, aptitude à libérer des peptides bioactifs inhibant lenzyme de conversion de langiotensine (ACE) responsable de lhypertension artérielle. Linvention concerne également des souches probiotiques de bactéries dacide lactique et les produits bactériens développés ayant des propriétés utiles. La souche probiotique incorporée Lactobacillus gasseri 7/12 NBIMCC No.
