Johann Wolfgang Goethe-Universitat Frankfurt am Main
发明人:
Ingrid FLEMING,Timo FRÖMEL,Jiong HU,Rüdiger POPP
申请号：
US16303940
公开号：
US20200317813A1
申请日:
2017.05.24
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention pertains to antagonists and inhibitors of soluble epoxide hydrolase (sEH) and 19,20-dihydroxydocosapentaenoic acid (19,20-DHDP) for use as a therapeutic in the treatment of eye disorders that are characterized by pericyte loss and motility. The invention is useful for treating the non-proliferative form of diabetic retinopathy. Furthermore provided are methods for monitoring or diagnosing diabetic retinopathy, in particular in subjects at risk of developing the disorder, for example diabetic patients.
