THANING, MIKKEL JACOB,OLSSON, ANDREAS,GLOGARD, CHRISTIAN
申请号:
CA2881853
公开号:
CA2881853A1
申请日:
2013.09.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to a process for the preparation of Ioforminol, a contrast agent useful in X-ray imaging. More particularly, the invention relates to preparation of Ioforminol from a compound mixture comprising 1-formylamino-3,5-bis(2,3-bis(formyloxy)propan-1-ylcarbamoyl)-2,4,6-trioodobenzene by a process comprising in situ hydrolysis and a bis-alkylation.