Formulations for oral transmucosal compositions including clomiphene-like selective estrogen receptor modulators (C-SERMs) in combination with transmucosal absorption enhancers are disclosed. Oral transmucosal compositions can be for fast release or slow release, and can be administered to induce ovulation in a female patient and thereby reduce symptoms of anovulatory infertility, unexplained infertility, and the like. Oral transmucosal compositions include liquid dosage forms, solid dosage forms, and chewing gums. Further dosage forms include mucoadhesive thin strips, thin films, tablets, patches, and tapes, among others. Other dosage forms are: mucoadhesive liquids, such as, for example gel-forming liquid gel-forming semisolids and gel-forming powders, among other dosage forms that exhibit mucoadhesive properties, and provide oral transmucosal delivery of C-SERMs. Oral transmucosal compositions will deliver C-SERMs directly into the patients bloodstream, and provide high bioavailability of C-SERMs therefore, the required doses are lower.
