ANDRE BUBENDORF,ANNETTE DEYNET-VUCENOVIC,RALPH DIODONE,OLAF GRASSMANN,KAI LINDENSTRUTH,EMMANUEL PINARD,FRANZISKA E. ROHRER,URS SCHWITTER
申请号:
BRPI0720829
公开号:
BRPI0720829A2
申请日:
2007.12.18
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.