The present invention relates to the amyloid beta peptide (Aβ) and more specifically to antibodies binding to Aβ protofibrils and their use in therapy and/or prophylactic treatment of Alzheimer's disease and other disorders associated with Aβ protein aggregation. Further the invention may relate to diagnosis of such diseases as well as monitoring of disease progression by use of the antibodies of the invention. Further, the invention may relate to veterinary use of the antibodies of the invention.本發明係關於類澱粉β肽(Aβ)且更具體而言結合至Aβ原纖維之抗體及其用於阿茲海默氏病(Alzheimer’s disease)及其他與Aβ蛋白質聚集相關之病症之療法及/或預防性治療之用途。此外,本發明係關於藉由使用本發明抗體診斷該等疾病以及監測疾病進展。另,本發明係關於本發明抗體之獸醫用途。