INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS
发明人:
MUNOZ RISUENO, RUTH
申请号：
CA2953272
公开号：
CA2953272A1
申请日:
2015.06.26
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention relates to a serotonin receptor (5-HTR) inhibitorselected from the group consisting of a type 1 5-HTR inhibitorand a type 2 5-HTR inhibitorfor use in the prevention and/or treatment of a haematological malignancy. Additionallly, the invention relates to in vitromethods for the identificationor isolation of a malignant cell from a haematological malignancy or for diagnosing a haematological malignancy based on detecting the expression of type 1 5-HTR and/or type 2 5-HTR.Furthermore, the invention relates to in vitromethods for determining the prognosis, for monitoring the effect of a therapy or for designing a customized therapy in a subject suffering from a haematological malignancy based on determining the levels of type1 5-HTRand/or type 2 5-HTR.
