Antibody-binding alpha4Beta7 integrin and its use in the treatment of inflammatory bowel disease

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专利权人:

Millennium Pharmaceuticals, Inc.;Genentech, Inc.

发明人:

Brettman, Lee R.,Fox, Judith A.,Allison, David Edward

申请号：

DK10010997

公开号：

DK2298348T3

申请日:

2001.04.13

申请国别(地区):

DK

年份:

2017

代理人:

摘要：

Disclosed is a method for treating a human having a disease associated with leukocyte infiltration of mucosal tissues, comprising administering to said human an effective amount of a human or humanized immunoglobulin or antigen-binding fragment thereof having binding specificity for ±4²7 integrin. Preferably, no more than about 8 mg immunoglobulin or fragment per kg body weight are administered during a period of about one month.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/