Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents

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专利权人:

MannKind Corporation

发明人:

Oberg, Keith A.

申请号：

AU2014271222

公开号：

AU2014271222B2

申请日:

2014.12.01

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2014271222B220160428.pdf#####METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF CRYSTALLINE MICROPARTICLE SURFACES FOR ACTIVE AGENTS ABSTRACT Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Type of surface properties that are altered by the disclosed methods include by electrostatic properties, hydrophobic properties and hydrogen bonding properties.

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