The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.本發明提供在結合於人類CD25之抗體中發現的抗體序列。特別地,本發明提供抗人類CD25抗體之序列,其不阻斷CD25與IL-2之結合或IL-2信號傳導。包括此序列之抗體及其抗原結合部分可用於醫藥組合物及治療方法中,特別是用於治療癌症。