The invention is directed to a Compound of Formula I, II, or III. The invention provides compounds that inhibit, regulate, and/or modulate PI3K that are useful in the treatment of hyperproliferatives diseases, such as cancer.Linvention concerne un composé de formule I, II, ou III. Les composés de linvention inhibent, régulent et/ou modulent lactivité de PI3K et sont utiles dans le traitement de maladies hyperprolifératives, comme le cancer.