Matthew J. Kipper,Nicole P. Ehrhart,Raimundo Romero,Timothy R. Gonzales
申请号:
US14496992
公开号:
US20150086602A1
申请日:
2014.09.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods of coating bone surfaces and coated bones comprising a coating comprising (a) a porous polysaccharide scaffold and/or a plurality of polysaccharide nanofibers and (b) a polyelectrolyte multilayer composition, are disclosed. The methods of coating bone surfaces and the coated bones disclosed provide a biomimetic periosteum to compensate for periosteum lost in preparing bone grafts, and the coated bone grafts, including allografts, restore lost osteogenic and osteoinductive qualities and improve clinical outcomes.