Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.本發明係揭示治療、預防及/或管控癌症，以及有關於或其特徵在於不想要的血管生成作用之疾病和病症的方法。該特定方法包括單獨或與第二個活性成分併用，投予免疫調節化合物。本發明進一步更關於降低或避免與化學療法、輻射療法、荷爾蒙療法、生物學療法或免疫療法有關之有害副作用的方法，其包括投予免疫調節化合物。亦揭示適用於本發明之方法的醫藥組合物、單一單位劑量形式和套組。
