PICKKERS, ROELOF PETER,MEHTA, RAVINDRA LALL,MURRAY, PATRICK THOMAS,JOANNIDIS, MICHAEL,VAN DEN BERG, ERIK JAN,AREND, JACQUES SALOMON ROBERT
申请号:
CA3093040
公开号:
CA3093040A1
申请日:
2019.03.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure relates to the use of alkaline phosphatases, and in particular improved alkaline phosphatases such as RecAP, for the prevention, treatment, cure, or amelioration of the symptoms of acute kidney injury caused, e.g., by sepsis. The application relates to methods of preserving renal function renal function, shortening the duration of renal replacement therapy, increasing the creatinine clearance, decreasing the risk of death in subjects with sepsis-associate acute kidney injury (SA-AKI) or at risk of SA-AKI.