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MEDICINE FOR GASTROESOPHAGEAL REFLUX DISEASE
专利权人:
ОНО ФАРМАСЬЮТИКАЛ КО.; ЛТД. (JP)
发明人:
ОКАДА Хироки (JP),КОНЕМУРА Такаси (JP)
申请号:
RU2015106931
公开号:
RU2015106931A
申请日:
2013.07.30
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. Means for suppressing transient relaxation of the lower esophageal sphincter containing 4 - [({6- [isobutyl (1,3-thiazol-2-ylsulfonyl) amino] -2,3-dihydro-1H-inden-5-yl} oxy) methyl] -3-methylbenzoic acid, its salt or its prodrug as an active ingredient. 2. The tool according to claim 1, which reduces the frequency of transient relaxation of the lower esophageal sphincter. 3. An agent for suppressing gastric acid reflux and / or stomach contents containing 4 - [({6- [isobutyl (1,3-thiazol-2-ylsulfonyl) amino] -2,3-dihydro-1H-inden-5-yl} hydroxy) methyl] -3-methylbenzoic acid, its salt or its prodrug as an active ingredient. 4. Means for preventing or preventing exacerbation of gastroesophageal reflux disease containing 4 - [({6- [isobutyl (1,3-thiazol-2-ylsulfonyl) amino] -2,3-dihydro-1H-inden-5-yl} oxy) methyl] -3-methylbenzoic acid, its salt or its prodrug as an active ingredient. 5. An agent for treating and / or improving a gastroesophageal reflux disease condition containing 4 - [({6- [isobutyl (1,3-thiazol-2-ylsulfonyl) amino] -2,3-dihydro-1H-inden-5-yl} hydroxy) methyl] -3-methylbenzoic acid, its salt or its prodrug as an active ingredient. 6. The agent of claim 5, wherein the gastroesophageal reflux disease is non-erosive. The agent of claim 5, wherein the symptoms of gastroesophageal reflux disease are heartburn and / or acid reflux. The tool according to any one of paragraphs. 5-7, where gastroesophageal reflux disease is resistant to a proton pump inhibitor. 9. The tool according to claim 5-7, which is used in combination with a drug selected from proton pump inhibitors, histamine H2 receptor antagonists, gastrointestinal prokinetics,1. Средство подавления транзиторного расслабления нижнего пищеводного сфинктера, содержащее 4-[({6-[изобутил(1,3-тиазол-2-илсульфонил)амино]-2,3-дигидро-1H-инден-5-ил}окси)метил]-3-метилбензойную кислоту, ее соль или ее пролекарство в качестве активного ингредиента.2. Средство по п. 1, которое уменьшает частоту транзиторно
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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