An intravascular stent, preparation method and use thereof. The intravascular stent includes a positioning segment and a supporting segment. The positioning segment includes a plurality of first repeating elements. The supporting segment includes at least two supporting units and at least one connecting unit. The supporting unit includes a plurality of second repeating elements. The number of the first repeating elements differing from the number of the second repeating elements. A plane formed by front ends of the plurality of first repeating elements being vertical to or intersecting with the axis of the intravascular stent. The intravascular stent is usable for iliac vein, with good supporting effect for iliac vein and less damage to venous wall, and can effectively avoid forming in-stent secondary thrombosis after intravascular stent implantation. Moreover, the intravascular stent is positionable in the iliac vein to improve the accuracy of the release.
