Vegf-binding molecules

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

GSCHWIND ANDREAS,BORGES ERIC,BOUCNEAU JOACHIM,DE TAVERNIER EVELYN,KOLKMAN JOOST,MERCHIERS PASCAL

申请号：

NZ60739411

公开号：

NZ607394A

申请日:

2011.09.02

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Discloses a VEGF-binding molecule comprising three CDR regions, wherein CDR1 is SYSMG, CDR2 is AISKGGYKYDAVSLEG, and CDR3 is SRAYGSSRLRLADTYEY, wherein the VEGF-binding molecule is capable of blocking the interaction of human recombinant VEGFR-2 with an inhibition rate of at least 60%, and related nucleic acids, vectors, host cells, pharmaceutical compositions and therapeutic uses.

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