LING HUANG,LESLIE S. JOHNSON,DERYK T. LOO,FRANCINE ZHIFEN CHEN,PAUL A. MOORE
申请号：
PT11751204
公开号：
PT2542256T
申请日:
2011.03.01
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
