A fluid delivery catheter 10 that uses micro-needles 36 for fluid delivery though a vessel wall. The catheter may provide fluid delivery therapy for various procedures, such as, for example, delivery of tumescent fluid or renal denervation. The catheter includes an elongate member 20 with deployable and retractable needles 36 disposed about a distal end of the elongate member. The needles may be disposed radially about the distal end and/or along a length of the distal end.