PURPOSE: A novel compound for hearing protection is provided to suppress an apoptotic mechanism of auditory hair cells and to protect an auditory system and hearing.CONSTITUTION: A novel compound for hearing protection is denoted by chemical formula 1. A method for preparing the compound of chemical formula 1 comprises: a step of reacting a compound of chemical formula 2 with 2-(4-fluorophenyl)acetyl chloride to prepare a compound of chemical formula 3 a step of reacting NaH with the compound of chemical formula 3 to prepare a compound of chemical formula 4 a step of reacting the compound of chemical formula 4 with SO_2Cl_2 to prepare a compound of chemical formula 5 a step of reacting NaH with the compound of chemical formula 5 to prepare a compound of chemical formula 6 and a step of reacting H_2 with the compound of chemical 6.COPYRIGHT KIPO 2013본 발명은 난청을 유발하는 다양한 이독성에 대해 청각유모세포의 세포사멸기전을 억제하고, 청각기관과 청력을 보호하는 본 명세서의 화학식 1로 표시되는 화합물, 이의 약학적으로 허용가능한 염, 및 이를 포함하는 조성물에 관한 것이다.
