Disclosed is a pharmaceutical composition with two components for use in the treatment, amelioration of symptoms, or both of Acquired Immune Deficiency Syndrome (AIDS) or a HIV infection in a subject comprising: -a sterile injectable polymannan extract formulation comprising one or more aloe polysaccharides, wherein the aloe polysaccharides comprise molecular weights ranging from 50,000-10,000,000 Daltons in an amount sufficient to treat or ameliorate symptoms of Acquired Immune Deficiency Syndrome (AIDS) or a HIV infection and a composition comprising: -one or more aloe anthraquinones, diacetyl anthraquinones, and combinations thereof -a freeze dried aloe powder, an aloe juice, an aloe gel, or a combination wherein the powder is administered as is or after reconstitution in a liquid and -one or more optional nutritional supplements selected from the group consisting of fatty acids, proteins, minerals and metals, vitamins, salts, amino acids, and one or more pharmaceutically acceptable excipients. Also disclosed is the use of such a composition for the manufacture of a medicament for treating, ameliorating symptoms or both of Acquired Immune Deficiency Syndrome (AIDS) or a HIV infection in a subject.
