MIAO, Zhenwei,CHEN, Gang,ZHU, Tong,KHASANOV, Alisher B.,HONG, Yufeng,CHUCHOLOWSKI, Alexander,ZHANG, Hong
申请号:
EP14854041
公开号:
EP3057610A4
申请日:
2014.10.15
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second drug conjugate with a different drug to a Lys residue on the targeting protein.