Tryptophan-2,3-dioxygenase (TDO) and / or indoleamine-2,3-dioxygenase (IDO) inhibitor compounds for use in medicine are provided, Wherein X 1 and X 2 may be the same or different and each is independently selected from C, N, O and S； X 3 , X 4 , X 5 , and X 6 may be the same or different and each is independently selected from C and N； Each bond represented by the dotted line may be present or absent, provided that at least one such bond is present； R 1 , R 2 , R 3 , R 4 , R 5 and R 6 may be present or absent and may be the same or different and each is independently selected from H and substituted or unsubstituted organic groups, The number of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 groups present is such that the valence of each of X 1 , X 2 , X 3 , X 4 , X 5 and X 6 is maintained； Wherein at least one of R <； 5 >； and R <； 6 >； comprises a group Y, wherein Y is a group having the formula selected from: Wherein L may be present or absent, and may be a substituted or unsubstituted organic linking group； R 31 and R 32 , which may be the same or different, are selected from H and substituted or unsubstituted organic groups； Each R 34 may be the same or different and is selected from H and substituted or unsubstituted organic groups； R 35 is selected from substituted or unsubstituted alcohol or ether groups； Each R 36 may be the same or different and is selected from H and substituted or unsubstituted organic groups； X 7 can be selected from C and N； X 8 , X 9 , X 10 , X 11 , X 12 , X 13 , X 14 , X 15 and X 16 may be the same or different and each is independently selected from C, N, O and S； Each bond represented by the dotted line may be present or absent； Each R 313 may be the same or different and is selected from H and substituted or unsubstituted organic groups.하기 화학식을 포함하는, 의약에 사용하기 위한 트립토판-2,3-디옥시게나제 (TDO) 및/또는 인돌아민-2,3-디옥시게나제 (IDO) 억제제 화합물이 제공된다.여기서 X1, 및 X2는 동일하거나 상이할 수 있으며, 각각은 독립적으로 C, N, O 및 S로부터 선택되고； X3, X4, X5, 및 X6은 동일하거나 상이할 수 있으며, 각각은 독립적으로
