Abstract: Apparati and methods are provided for the delivery of molecules to a site via a carrier fluid. The apparati include microchip devices whcih have reservoirs containing the molecules for release. The apparati and methods provide for active orpassive controlled relase of the molecules. Preferred embodiments include systems for intravenous administration of drugs, wherein drug molecules are released from the microchip devices into a carrier fluid ex vivo, such as a saline solution, forming a drug/saline solution mixture which is then delivered to a patient intravenously.
