CHAO, JUI I,赵瑞益,趙瑞益,WANG, SU PEI,王舒霈,王舒霈,CHEN, CHINPIAO,陈清漂,陳清漂,YIN, KAI HAO,殷凯浩,殷凱浩,YANG, JINN MOON,杨进木,楊進木,WU, YA HUI,吴雅惠,吳雅惠
申请号:
TW103130727
公开号:
TWI567063B
申请日:
2014.09.05
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
This invention provides a compound of Formula (I) and salt thereof, wherein, m is an integer of 2 to 7, and R is independently at least one selected from the group consisting of hydrogen and C1-C20 alkyl groups. The compound promotes apoptosis in cancer cells and inhibits their growth. This invention also provides a pharmaceutical composition which comprises the compound of Formula (I), salt thereof and pharmaceutically acceptable carriers. This invention further provides uses for production of the pharmaceutical composition used for treating cancer.本發明係提供一種式(I)化合物或其鹽,其中,m為2至7之整數,以及R係獨立選自由氫及C1-C20烷基所組成群組之至少一者。該化合物係用以促進癌細胞的細胞凋亡,以抑制癌細胞的生長。本發明進一步提供一種醫藥組成物,該醫藥組成物係包含式(I)之化合物或其鹽以及醫藥上可接受之載劑。本發明再進一步提供一種包含式(I)之化合物或其鹽的用途,係用於製造治療癌症之藥物。