A pharmaceutical dosage form such as a capsule, a conventional or orally disintegratingtablet capable of delivering a nitrogen (N)-containing therapeutic agent havinga pKa in the range of from about 5 to 14 into the body in a sustained- released fashion,in order to be suitable for a twice- or once-daily dosing regimen, comprises atleast one organic acid, which solubilizes the therapeutic agent the drug priorto releasing it into the hostile intestinal environment wherein said weaklybasic drug is practically insoluble. The unit dosage form is composed of a multitudeof multicoated particulates (