Young-Sup Yoon,Xiaodong Cheng,Ji Woong Han,Antonello Mai
申请号：
US14356024
公开号：
US09458131B2
申请日:
2012.11.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This disclosure relates to compounds, compositions and methods of epigenetically transforming cells. In certain embodiments, the disclosure relates to methods of generating epigenetically altered cells comprising mixing isolated cells with compositions disclosed herein under conditions such that epigenetically altered cells are formed. In certain embodiments, the disclosure contemplates inducing cells, such as adult somatic cells or cells that are not naturally pluripotent, into cells with chemically induce pluripotency. In certain embodiments, the disclosure contemplates certain compounds disclosed herein, compounds disclosed herein optionally substituted with one or more substituents, derivatives, or salts thereof, for these purposes.
