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Peptide for inhibiting vascular endothelial growth factor receptor
专利权人:
The University of Tokyo;Peptidream Inc.
发明人:
Hiroshi Murakami,Takashi Kawakami,Takahiro Ishizawa,Hiroaki Suga,Patrick Reid
申请号:
US14424192
公开号:
US09815867B2
申请日:
2013.09.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
An object of the present invention is to provide a VEGFR2 inhibitor peptide having high specificity and available at a low cost. The present invention provides a peptide having the following amino acid sequence:Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11-Xaa12-Xaa13-Xaa14-Xaa15[wherein, Xaa2 represents Val or derivative thereof, Xaa6 represents Asp or derivative thereof, Xaa7 represents Pro or derivative thereof, Xaa8 represents Trp or derivative thereof, Xaa10 represents Asn or derivative thereof, Xaa11 represents Gly or derivative thereof, Xaa12 represents Leu or derivative thereof, Xaa1, Xaa3 to Xaa5, Xaa9, and Xaa13 to Xaa15 each independently represent an arbitrary amino acid or derivative thereof]; orXaa16-Xaa17-Xaa18-Xaa19-Xaa20-Xaa21-Xaa22-Xaa23-Xaa24-Xaa25-Xaa26-Xaa27-Xaa28-Xaa29-Xaa30[wherein, Xaa24 represents His or derivative thereof, Xaa25 represents Pro or derivative thereof, and Xaa16 to Xaa23 and Xaa26 to Xaa30 each represent an arbitrary amino acid].
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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