The present invention relates to a new microporous zirconium silicate composition formulated to remove toxins such as potassium ions from the gastrointestinal tract at an increased rate, but without causing undesirable side effects. A preferred composition has at least 95% ZS-9. These compositions are particularly useful for therapeutic treatment of hyperkalemia. These compositions can also be used to treat chronic kidney disease, coronary artery disease, diabetes, and graft rejection.本發明涉及新的微孔矽酸鋯組合物,將其配製成可從胃腸道中以升高的速率除去毒素如鉀離子,但不會導致不期望的副作用。優選的組合物具有至少95%ZS‑9。這些組合物特別地可用於治療性治療高鉀血症。這些組合物還可用於治療慢性腎疾病、冠狀血管疾病、糖尿病和移植物排斥。