An occipital plate for occipito-cervical fixation comprising a substantially flat plate (2) provided with at least one fixation area (2a) connectable to the skull of a patient and at least one pair of through slots (2b) extending length-wise away from each other, at least one pair of clamps (3) slidably constrained each in a respective slot (2b) to move along a medial-lateral adjustment direction (A) and provided with respective seats (4) for receiving a support bar (101), wherein each receiving seat (4) has an opening (4a) for insertion of the respective support bar (101) accessible laterally and/or longitudinally along an insertion direction (B) substantially parallel to a lying plane (P) of said plate (2).