Sang Hee Park,Jun Ok Moon,Sang Jo Lim,Do Hyun Kwon,Kyung Han Lee,Jin Suck Sung,Hyun Joon Kim
申请号:
US14362036
公开号:
US20140356518A1
申请日:
2012.10.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to a method for producing highly-concentrated L-amino acid and riboflavin simultaneously, and a microorganism for simultaneously producing L-amino acid and riboflavin. Specifically, the present invention relates to a modified microorganism for producing L-lysine or L-threonine, and riboflavin simultaneously, wherein the microorganism belonging to Corynebacterium sp. capable of producing L-lysine or L-threonine is modified by enhancing the activity of an enzyme family expressed by a rib operon which contains riboflavin biosynthesis gene family. Also, the present invention relates to a method for the simultaneous production of L-lysine or L-threonine, and riboflavin using the modified microorganism, and relates to a formulation or granular formulation, feed, and feed additive, containing L-lysine or L-threonine, and riboflavin produced from a culture medium of the modified microorganism.