Provided is a curable orthopedic splint. The curable orthopedic splint includes: an inner shell contacting a bone fracture site, an outer shell bonded to the inner shell, a curable core accommodated between the inner shell and the outer shell, the curable core being cured to match a shape of the bone fracture site, and a fixing holder contacting a surface of the outer shell to surrounding the curable core and the bone fracture site, the fixing holder having both ends that are detachably bonded to each other or detachably bonded to the surface of the outer shell so as to closely attach and fix the curable core to the bone fracture site.