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DE NOVO BINDING DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF
专利权人:
ARCELLX, INC;SUBDOMAIN, LLC
发明人:
David William LAFLEUR,David M. HILBERT
申请号:
US15564325
公开号:
US20180251521A1
申请日:
2016.04.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such libraries and screens are also encompassed. Methods of making and using the DBDpp are additionally provided. Such uses include, without limitation, affinity purification, and diagnostic and therapeutic applications.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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