UTILISATION DE SHROOM3 DANS UNE MALADIE RENALE CHRONIQUE ET UNE NEPHROPATHIE D'ALLOGREFFE CHRONIQUE

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专利权人:

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

发明人:

MURPHY, BARBARA,HE, CIJIANG

申请号：

CA2904600

公开号：

CA2904600A1

申请日:

2014.03.10

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

A method for identifying the risk of developing Chronic Allograft Nephropathy (CAN) in a patient that received a kidney transplant from a donor which comprises identifying the race of the donor； determining the levels of SHROOM 3 expression in a kidney biopsy specimen obtained from the patient at a predetermined time after transplant； comparing the level of SHROOM 3 expression in the biopsy specimen with the levels of SHROOM 3 expression in a control； determining if the level of SHROOM 3 expression in the allograft is significantly higher than in the control, and diagnosing the patient as being at risk for CAN if the level of SHROOM 3 expression in the specimen is significantly higher than in the control.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/