Scott A. Guelcher,Joseph C. Wenke,Carlos C. Sanchez, Jr.,Kevin S. Akers,Chad A. Kruger,Edna M. Prieto,Katarzyna Zienkiewicz
申请号：
US14420625
公开号：
US20150182667A1
申请日:
2013.08.08
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Embodiments of the presently-disclosed subject matter provide composites that comprise a tissue graft and a biofilm dispersal agent. The tissue graft can be bone tissue graft, a soft tissue graft, or the like. In specific embodiments the tissue graft is a polyurethane graft and in other embodiments the tissue graft is bone particles, such as demineralized bone matrix. The biofilm dispersal agent can be one or more D-amino acids. The presently-disclosed subject matter further includes methods for treating tissue of a subject that comprise administering the present composites as well as methods for manufacturing the present composites.
