GAUDET, Francois,ATTAR, Ricardo,HARMAN, Benjamin C.,LI, Yingzhe,LUO, Jinquan,MCDAID, Ronan,POMERANTZ, Steven C.,TAM, Susan H.,TEPLYAKOV, Alexey,WHEELER, John,WU, Sheng-Jiun,NEMETH, Jennifer F.
申请号：
PE0003972017
公开号：
PE15562017A1
申请日:
2015.09.03
申请国别(地区):
PE
年份:
2017
代理人:
摘要：
Referring to Antibodies or Antigen binding Fragments that bind to these inmunoespecificamente CD123 SP2 (IL - 3rd) and CD123 SP1 (il3ra), being useful in the diagnosis, Treatment and monitoring of cancer progression, Regression or stability of CD123 expression.It also relates to polynucleotides that encode specific Antibodies of CD123 cells that Express Antibodies, as well as Related vectorsReferida a anticuerpos o fragmentos de union al antigeno de estos que se unen inmunoespecificamente a CD123 SP2 (IL-3Ra) y CD123 SP1 (IL3Ra), siendo utiles en el diagnostico, tratamiento o monitoreo de la progresion, regresion o estabilidad del cancer que expresa CD123. Tambien se refiere a polinucleotidos capaces de codificar los anticuerpos especificos de CD123, celulas que expresan los anticuerpos, asi como vectores relacionados
