METHOD FOR TREATING INFLAMMATION, ARTHRITIS OR DISC DISEASES USING A MIXED EXTRACT OF CIBOTII RHIZOMA, LEDEBOURIELLAE RADIX, ACHYRANTHIS RADIX, PAEONIA LACTIFLORA PALL AND GLYCYRRHIZAE RADIX
The present invention relates to a method for treating inflammation, arthritis or disc diseases using a pharmaceutically effective amount of a mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radixaccording to the present invention, and since the mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix increased the survival rate of macrophages in vitro, decreased the production of NO, which is involved in anti-inflammation, inhibited all of COX-2, iNOS and MMP expressions, showed nerve cell regenerative and protective effects, exhibited pain-inhibitory effect and arthritis edema-inhibitory effects in vivo, and showed disc volume decrease and absorption effect in patients of disc diseases, the mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix could be used effectively for methods for treating inflammation, arthritis, or disc diseases.
