Shanghai Genon Bioengineering Co., Ltd;Shanghai Transgenic Research Center
发明人:
申请号：
EP13894189.3
公开号：
EP3050964A4
申请日:
2013.09.28
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Provided in the present invention is a method for positioning and integrating transgene and a use thereof. Specifically provided is a variant loxP element. The sequence "ATAAT" of an reverse repeated sequence in a wild type loxp locus is mutated into "CACCT", i.e., a variant loxp element. Also provided in the present invention are a construct comprising the variant loxP element, a vector or host cell comprising the construct and a method for preparing a transgenic animal using the vector and the host cell.
