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Formulation destinée à la libération contrôlée d'interferone par un copolymère bloc
专利权人:
BIOLEX THERAPEUTICS; INC.
发明人:
申请号:
EP07120539.7
公开号:
EP1886668B1
申请日:
2006.01.06
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention discloses a pharmaceutical composition for the controlled release of relatively toxic active compounds, in particular for bioactive proteins from the class of interferons. The composition comprises a biodegradable block copolymer constructed from poly(ethylene glycol) terephthalate (PEGT) and poly(butylene terephthalate) (PBT). The composition is provided in the form of injectable microparticles, of an injectable liquid which may have self-gelling properties, or of a solid implant. The invention further provides a pharmaceutical kit comprising the composition, methods for preparing the composition, and the pharmaceutical uses relating thereto.
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